ea0033p64 | (1) | BSPED2013
Carolan Eirin
, Hogan Andrew
, Corrigan Michelle
, O'Connell Jean
, Foley Niamh
, O'Neill Luke
, Cody Declan
, O'Shea Donal
Background: Although the association between obesity, chronic low-grade inflammation and immune dysregulation is well described in adults, there is a paucity of literature regarding this in children. We hypothesized that childhood obesity is associated with significant immune dysregulation.Methods: Expression of cytokines and microRNAs (miR) involved in the pathogenesis of metabolic disease were assessed in 49 participants aged 618 years. Invariant...